Key result
Higher global heart rate variability and parasympathetic tone on day 1 were significantly associated with progression to brain death in patients with severe head trauma.
Why the study?
Does heart rate variability predict evolution to brain death and neurologic outcome in patients with severe head injury?
Population
20 patients with severe head trauma (Glasgow Coma Scale [GCS] ≤ 8)
Comparison
Heart rate variability analysis via 24-hour… vs Survivors vs patients progressing to brain…
Design
Cohort
Follow-up
Awakening period (at least 5 days)
Authors
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May inform early risk stratification in head trauma; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=20)
Does heart rate variability predict evolution to brain death and neurologic outcome in patients with severe head injury?
Heart rate variability analysis may serve as a useful noninvasive predictor of imminent brain death and neurologic outcome in patients with severe head trauma.
Rapenne et al. (2001) conducted an observational in Severe head injury (n=20). Heart rate variability (HRV) vs. Survivors or patients with good recovery was evaluated on Progression to brain death and neurologic recovery. Higher global heart rate variability and parasympathetic tone on day 1 were significantly associated with progression to brain death in patients with severe head trauma.
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