Why the study?
Targeted temperature management with sedation or neuromuscular blockade affects early prognostication after sudden cardiac arrest, prompting investigation into whether heart rate variability analysis can prognosticate poor neurological outcome.
Does heart rate variability analysis predict poor neurological outcome in comatose adult patients with out-of-hospital sudden cardiac arrest undergoing hypothermic targeted temperature management?
Comparison
Good outcome (GOS 1-2) vs poor outcome (GOS 3-5)
Design
Prospective cohort study
Follow-up
2 weeks after ROSC
Authors
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May aid early prognostication accuracy after cardiac arrest with TTM; leaves open whether it should alter WLST timing.
Does heart rate variability analysis predict poor neurological outcome in comatose adult patients with out-of-hospital sudden cardiac arrest undergoing hypothermic targeted temperature management?
Heart rate variability analysis, specifically ln VLF power and DFA (α1), can be a useful tool for early prognostication of poor neurological outcome in comatose patients after out-of-hospital cardiac arrest undergoing hypothermic targeted temperature management.
Endoh et al. (2019) studied this question.
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