Why the study?
Does inhibition of the renin-angiotensin system, the endothelin system, or statin therapy improve vascular function in atherosclerosis?
Does inhibition of the renin-angiotensin system, the endothelin system, or statin therapy improve vascular function in atherosclerosis?
Therapies targeting endothelial dysfunction, such as renin-angiotensin system inhibitors and statins, improve vascular function and may reduce cardiovascular complications in atherosclerosis.
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May support RAS inhibitors or statins for endothelial dysfunction in atherosclerosis; leaves open confirmation in prospective outcome trials.
Barton et al. (2001) studied this question.
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