Why the study?
Does the use of dynamic indicators and dynamic arterial elastance improve the prediction of cardiac output and mean arterial pressure response to intravenous fluid therapy in surgical patients?
Does the use of dynamic indicators and dynamic arterial elastance improve the prediction of cardiac output and mean arterial pressure response to intravenous fluid therapy in surgical patients?
Dynamic indicators of fluid responsiveness and dynamic arterial elastance provide better functional assessment for guiding intravenous fluid therapy in hypotensive surgical patients than static preload indicators.
Dynamic indicators may better predict fluid responsiveness than static measures; leaves open randomized outcome trials in surgical patients.
Management with intravenous fluids can improve cardiac output in some surgical patients. Management with static preload indicators, such as central venous pressure and pulmonary artery occlusion pressure, has not demonstrated a suitable relationship with changes in the cardiac output induced by intravenous fluid therapy. Dynamic indicators, such as the variability of arterial pulse pressure or stroke volume variation, have demonstrated a suitable relationship. Since improvement in cardiac output does not guarantee an adequate perfusion pressure, in patients with hypotension, it is also necessary to know whether arterial pressure will also increase with intravenous fluid therapy. In this regard, the functional assessment of arterial load by dynamic arterial elastance could help to determine which patients will improve not only their cardiac output but also their mean arterial pressure.
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Sánchez et al. (2017) studied this question.
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