Population
Isolated segments of human peripheral arteries and veins
Comparison
Prostaglandin F2alpha (PGF2alpha 2.8 X 10 -- 2.8… vs Noradrenaline and potassium
Design
Preclinical
Authors
Loading...
Animal vessel data on PGF2α contractility require human validation; leaves open translation to clinical vascular pharmacology.
PGF2alpha induces concentration-dependent contraction in human peripheral arteries and veins, likely by enhancing transmembrane calcium flow and facilitating calcium release from intracellular stores.
Mikkelsen et al. (1978) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: