Why the study?
Does point-of-care coagulation testing reduce blood loss and transfusion requirements in patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
Patients undergoing cardiac surgery with cardiopulmonary bypass at risk for excessive perioperative blood loss
Comparison
Point-of-care coagulation assays for… vs Standard laboratory-based tests and empiric…
Design
Review
Authors
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May support POC-guided heparin management to limit transfusions in CPB; leaves open need for RCTs before practice change.
Does point-of-care coagulation testing reduce blood loss and transfusion requirements in patients undergoing cardiac surgery with cardiopulmonary bypass?
Point-of-care coagulation testing in cardiac surgery with cardiopulmonary bypass may facilitate targeted therapy and reduce excessive blood loss and transfusion requirements compared to empiric treatment.
Despotis et al. (1997) studied this question.
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