Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations.

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Demonstration, by somatic cell genetics, of coordinate regulation of genes for two enzymes of purine synthesis assigned to human chromosome 21.1981 · 94 citations
2. 2NAD-dependent methylenetetrahydrofolate dehydrogenase is expressed by immortal cells.1985 · 97 citations
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4. 4A somatic cell hybrid with a single human chromosome 22 corrects the defect in the CHO mutant (Ade ^– I) lacking adenylosuccinase activity2008 · 56 citations
5. 5A DNA sequence conferring high postmeiotic segregation frequency to heterozygous deletions in Saccharomyces cerevisiae is related to sequences associated with eucaryotic recombination hotspots.1988 · 33 citations