Why the study?
Preinjury DOAC therapy poses challenges in trauma and acute care surgery, requiring rapid identification to guide timely reversal of factor Xa and direct thrombin inhibitors.
Does point-of-care viscoelastic testing with the TEG 6s system accurately detect and classify DOACs in patient blood samples?
Population
Patients with and without DOAC treatment, and healthy volunteers
Comparison
Patients with DOAC treatment vs without DOAC treatment and healthy volunteers
Design
Observational, prospective, open-label, multicenter study
Authors
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May enable rapid DOAC reversal decisions in trauma; leaves open need for prospective outcome trials.
Does point-of-care viscoelastic testing with the TEG 6s system accurately detect and classify DOACs in patient blood samples?
The TEG 6s point-of-care system can rapidly and accurately detect and classify DOACs, potentially guiding timely reversal strategies in acute care settings.
Dias et al. (2019) studied this question.
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