What question did this study set out to answer?

The aim is to investigate the presence of antibodies in patients with practolol-induced eye damage and compare their binding properties to those in pemphigus.

March 15, 1975BMJOpen Access

Untoward effects associated with practolol: demonstration of antibody binding to epithelial tissue.

View Full Paper

Ask AI

Bookmark

Authors

HAH. AmosUniversity of Cambridge WBW D BrigdenRoyal Berkshire Hospital RMR. A. McKERRONSt. John's University

Discussion

Member takes

Implication

Demonstrates findings on antibody binding associated with practolol-induced eye damage, highlighting potential implications for treatment.

Key Points

The aim is to investigate the presence of antibodies in patients with practolol-induced eye damage and compare their binding properties to those in pemphigus.
Utilized indirect immunofluorescence to detect antibodies in patient serum.
Compared binding abilities of antibodies from practolol patients and pemphigus patients to isolated epidermal cells.
Antibodies in patients with practolol-induced eye damage bound to intercellular regions of epidermal tissue.
Binding was not observed for practolol antibodies when compared to pemphigus antibodies, suggesting differing specificities.

Cite This Study

Amos et al. (1975) studied this question.

synapsesocial.com/papers/6a6fa1cbabc331a858078f91 https://doi.org/10.1136/bmj.1.5958.598

View Full Paper

Ask AI

Bookmark

Implication

Demonstrates findings on antibody binding associated with practolol-induced eye damage, highlighting potential implications for treatment.

Untoward effects associated with practolol: demonstration of antibody binding to epithelial tissue.

Discussion

Member takes

Implication

Key Points

Cite This Study

Untoward effects associated with practolol: demonstration of antibody binding to epithelial tissue.

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider