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November 9, 1974BMJOpen Access

Cutaneous and Ocular Reactions to Practolol

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Authors

RFR FelixUniversitätsklinik für StrahlentherapieFIF. A. IveUniversity Hospital of North DurhamMDM.G.C. DahlWillamette University

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Implication

Case series reveals diverse cutaneous eruptions and persistent ocular damage in patients receiving practolol, highlighting severe adverse drug toxicity.

Key Points

  • To document and characterize the clinical features of cutaneous and ocular adverse reactions linked to practolol administration.
  • Clinical evaluation of patients presenting with practolol-induced dermatological reactions over a two-year period (N=21).
  • Morphological characterization of skin lesions and screening for associated ocular complications.
  • Cutaneous manifestations presented with diverse morphologies resembling eczema, lupus erythematosus, lichen planus, and a distinct toxic erythematous psoriasiform eruption.
  • Persistent ocular damage occurred in 3 of 21 patients (14.3%).

Cite This Study

Felix et al. (1974) studied this question.

synapsesocial.com/papers/6a6fec09ac440176ef2892c8https://doi.org/10.1136/bmj.4.5940.321
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Practolol in Treatment of Angina Pectoris. A Double-blind Trial1970 · 36 citations
  2. 2Clinical Evaluation of Practolol, a New Cardioselective Beta-blocking Agent in Angina Pectoris1970 · 36 citations