Effect of the ratio of coronary arterial lumen volume to left ventricle myocardial mass derived from coronary CT angiography on fractional flow reserve
Why the study?
Does a lower ratio of coronary arterial lumen volume to left ventricular myocardial mass (V/M) predict lower fractional flow reserve (FFR) in patients with suspected CAD?
Population
238 patients with suspected coronary artery disease from the NXT trial who underwent coronary computed…
Comparison
Low ratio of total epicardial coronary arterial… vs High V/M ratio
Design
Cohort
Authors
Discussion
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Member takes
Implication
May refine CTA-based ischemia assessment; leaves open whether V/M improves outcomes or revascularization decisions.
Structured PICO
Does a lower ratio of coronary arterial lumen volume to left ventricular myocardial mass (V/M) predict lower fractional flow reserve (FFR) in patients with suspected CAD?
P
Population
238 patients with suspected coronary artery disease (CAD) from the NXT trial who underwent coronary computed tomography angiography (CTA), quantitative coronary angiography (QCA), and fractional flow reserve (FFR) measurement in 438 vessels.
I
Intervention
Low ratio of total epicardial coronary arterial lumen volume to left ventricular myocardial mass (V/M) derived from coronary CTA
C
Comparator
High V/M ratio
O
Outcome
Fractional flow reserve (FFR)surrogate
A lower ratio of coronary arterial lumen volume to left ventricular myocardial mass derived from CTA is an independent predictor of lower FFR, even in non-obstructive CAD.
Cite This Study
Taylor et al. (2017) studied this question.