Computed tomography derived fractional flow reserve testing in stable patients with typical angina pectoris: influence on downstream rate of invasive coronary angiography
Why the study?
Does frontline coronary CTA with selective FFRCT testing safely reduce downstream invasive coronary angiography in stable patients with typical angina pectoris?
Population
774 stable patients referred to non-emergent invasive coronary angiography or coronary CTA on suspicion of…
Design
Cohort
Follow-up
mean 157 ± 50 days
Authors
Discussion
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Member takes
Implication
May support frontline CTA with selective FFRCT in typical angina; leaves open need for RCTs to confirm downstream ICA reduction.
Structured PICO
Does frontline coronary CTA with selective FFRCT testing safely reduce downstream invasive coronary angiography in stable patients with typical angina pectoris?
P
Population
774 stable patients referred to non-emergent invasive coronary angiography (ICA) or coronary CTA on suspicion of CAD, divided into low-intermediate-risk (n=593) and high-risk (n=181) with typical angina pectoris.
I
Intervention
Frontline coronary CTA with selective CT-derived fractional flow reserve (FFRCT) testing
O
Outcome
Downstream testing (ICA) and treatment within 3 months, and adverse events ≥90 dayssafety
Frontline coronary CTA with selective FFRCT testing safely reduces the need for invasive coronary angiography in stable patients with typical angina.
Cite This Study
Jensen et al. (2017) studied this question.