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March 24, 2021Medical VisualizationOpen Access

MRI- and CT-venography in the diagnosis of hemodynamic disorders in patients suffering from lower extremities chronic venous disorders. Part II. Possibilities of MRI in diagnostics of the deep vein thrombosis

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Authors

ESE. V. ShajdakovInstitute of the Human BrainASA. B. SannikovPrivolzhsky Research Medical UniversityVEV. M. EmelyanenkoPirogov Russian National Research Medical University

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Overview

Literature review reveals strong diagnostic accuracy for magnetic resonance venography in deep vein thrombosis, suggesting wider clinical adoption is warranted.

Key Points

  • Evaluate the clinical utility, methodological evolution, and diagnostic performance of magnetic resonance venography modalities for detecting lower extremity deep vein thrombosis and chronic venous disorders.
  • Reviewed literature evaluating non-contrast and contrast-enhanced magnetic resonance venography (MRV) applied to the inferior vena cava and lower limb venous systems.
  • Assessed technical parameters of non-contrast modalities including time-of-flight (TOF), phase contrast (PC), and direct thrombus imaging (MRDTI) sequences.
  • Analyzed contrast agents, pulse sequence safety profiles, image post-processing techniques, and diagnostic sensitivity and specificity metrics.
  • Non-contrast MRV approaches, particularly magnetic resonance direct thrombus imaging (MRDTI) with bSSFP and DANTE sequences, demonstrated high diagnostic value without exogenous agent risks.
  • Contrast-enhanced MRV provided superior visualization and higher signal-to-noise ratios using cyclic gadolinium or iron-oxide blood pool agents, avoiding safety restrictions linked to linear gadolinium agents.
  • Both contrast-free and contrast-enhanced MRV demonstrated robust diagnostic sensitivity and specificity for identifying lower extremity deep vein thrombosis.

Cite This Study

Shajdakov et al. (2021) studied this question.

synapsesocial.com/papers/6a6fa2d726a7f98052dc43b8https://doi.org/10.24835/1607-0763-901
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