What question did this study set out to answer?

The study investigates the relationship between intraventricular filling velocities and left ventricular systolic function in coronary artery disease.

March 1, 1994European Heart Journal

Chrome congestive heart failure

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Why the study?

Does colour M-mode Doppler assessment of intraventricular early filling velocities detect delayed apical filling in patients with coronary artery disease?

Population

161 individuals, comprising 54 healthy individuals and 107 patients with coronary artery disease.

Comparison

Colour M-mode Doppler assessment of… vs Healthy reference group and patients with…

Design

Cross-sectional

Authors

MSMarie StugaardUniversity of Oslo UBU. BrodahlOslo University Hospital HTHans TorpCardiac Imaging

Discussion

Member takes

Implication

May identify delayed apical filling linked to LV dysfunction severity in CAD; hypothesis-generating for colour M-mode Doppler, needs prospective validation.

Key Points

The study investigates the relationship between intraventricular filling velocities and left ventricular systolic function in coronary artery disease.
Measured intraventricular early filling velocities in 161 individuals using colour M-mode Doppler by dividing mitral to apical distances.
Divided patients based on systolic function assessed through left ventriculography.
Compared normalized time differences and transmitral velocity ratios among different patient groups.
Normalized time difference was similar in healthy individuals (12 +/- 8 ms.cm-1) and patients without infarction (16 +/- 16 ms.cm-1).
Significantly increased in patients with infarction/regional dysfunction (43 +/- 21 ms.cm-1) and further in those with severe impairment (53 +/- 14 ms.cm-1).
Transmitral peak early and late velocity ratio decreased in patients with regional dysfunction but normalized in severely impaired ventricles.

Structured PICO

Does colour M-mode Doppler assessment of intraventricular early filling velocities detect delayed apical filling in patients with coronary artery disease?

Population

161 individuals, comprising 54 healthy individuals and 107 patients with coronary artery disease.

Intervention

Colour M-mode Doppler assessment of intraventricular early filling velocities (calculating the normalized time difference between the occurrence of peak velocity in the apical region and at the mitral tip).

Comparator

Healthy reference group and patients with coronary artery disease with no electrocardiographical signs of previous infarction and normal ventriculography.

Outcome

Normalized time difference between the occurrence of peak velocity in the apical region and at the mitral tip.surrogate

Colour M-mode Doppler demonstrates that apical filling is delayed in patients with left ventricular injury due to coronary artery disease, and this delay worsens with the progression of ventricular injury.

Cite This Study

Stugaard et al. (1994) studied this question.

synapsesocial.com/papers/6a6fa3d65d37378ac1dcb35d https://doi.org/10.1093/oxfordjournals.eurheartj.a060497

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Implication

May identify delayed apical filling linked to LV dysfunction severity in CAD; hypothesis-generating for colour M-mode Doppler, needs prospective validation.

Chrome congestive heart failure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Chrome congestive heart failure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

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