Why the study?
Is the Nexgen prosthesis more cost-effective than other commonly used prosthesis brands for total knee replacement in patients with osteoarthritis?
Population
239,945 patients aged 55 to 84 years who had a primary, unilateral total knee replacement for osteoarthritis…
Comparison
Nexgen cemented unconstrained fixed bearing… vs Other commonly used prosthesis brands
Design
Cohort
Follow-up
Up to 10 years for revision rates; lifetime for Markov model
Authors
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Nexgen may offer best value among common TKR brands; leaves open need for RCTs before changing prosthesis selection.
Is the Nexgen prosthesis more cost-effective than other commonly used prosthesis brands for total knee replacement in patients with osteoarthritis?
Nexgen prostheses provide improved patient outcomes at a low additional cost compared to other brands, making it a highly cost-effective first-choice prosthesis for total knee replacement in osteoarthritis.
Pennington et al. (2016) studied this question.
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