Why the study?
Studies evaluating the acute effect of postprandial exercise on glucose responses show significant heterogeneity regarding participant demographics, exercise protocols, and timing post-meal.
Does postprandial exercise reduce postprandial glucose AUC and 24 h mean glucose levels in overweight individuals and individuals with obesity and type 2 diabetes?
Does postprandial exercise reduce postprandial glucose AUC and 24 h mean glucose levels in overweight individuals and individuals with obesity and type 2 diabetes?
Postprandial exercise significantly reduces glucose AUC and 24-hour mean glucose levels in overweight/obese individuals and those with T2DM, with greater effects seen with longer duration (>30 min) and delayed initiation (≥60 min post-meal).
PPE reduces glucose AUC and 24-h levels in overweight/T2DM adults; supports its integration into glycemic strategies while calling for refined timing and duration trials.
Studies investigating the acute effect of postprandial exercise (PPE) on glucose responses exhibit significant heterogeneity in terms of participant demographic, exercise protocol, and exercise timing post-meal. As such, this study aimed to further analyze the existing literature on the impact of PPE on glycemic control in overweight individuals and individuals with obesity and type 2 diabetes (T2DM). A literature search was conducted through databases such as PubMed, CINAHL, and Google Scholar. Thirty-one original research studies that met the inclusion criteria were selected. A random-effect meta-analysis was performed to compare postprandial glucose area under the curve (AUC) and 24 h mean glucose levels between PPE and the time-matched no-exercise control (CON). Subgroup analyses were conducted to explore whether the glucose-lowering effect of PPE could be influenced by exercise duration, exercise timing post-meal, and the disease status of participants. This study revealed a significantly reduced glucose AUC (Hedges’ g = −0.317; SE = 0.057; p < 0.05) and 24 h mean glucose levels (Hedges’ g = −0.328; SE = 0.062; p < 0.05) following PPE compared to CON. The reduction in glucose AUC was greater (p < 0.05) following PPE lasting >30 min compared to ≤30 min. The reduction in 24 h mean glucose levels was also greater (p < 0.05) following PPE for ≥60 min compared to <60 min post-meal and in those with T2DM compared to those without T2DM. PPE offers a viable approach for glucose management and can be performed in various forms so long as exercise duration is sufficient. The glucose-lowering effect of PPE may be further enhanced by initiating it after the first hour post-meal. PPE is a promising strategy, particularly for patients with T2DM. This manuscript is registered with Research Registry (UIN: reviewregistry1693).
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Kang et al. (2023) studied this question.
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