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December 1, 1983Journal of Biological ChemistryOpen Access

Boundaries of gene conversion within the duplicated human alpha-globin genes. Concerted evolution by segmental recombination.

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Authors

AMAlan M. MichelsonBoston Children's Hospital
Stuart H. Orkin
Stuart H. OrkinBroad Institute

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Michelson et al. (1983) studied this question.

synapsesocial.com/papers/6a6fa9b8e5469ee92be0899fhttps://doi.org/10.1016/s0021-9258(17)43800-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evolution of Repeated DNA Sequences by Unequal Crossover1976 · 1,251 citations
  2. 2The duplicated human alpha globin genes lie close together in cellular DNA.1978 · 176 citations
  3. 3Hybrid DNA formation during meiotic recombination.1981 · 28 citations
  4. 4Gene conversion of two functional goat alpha-globin genes preserves only minimal flanking sequences.1982 · 91 citations
  5. 5Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.1979 · 181 citations