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This research aims to quantitatively assess the impact of zinc oxide supplementation on fermentation characteristics and productivity in ruminants.

The Influence of Zinc Oxide Utilization in Ruminants: A Systematic Review and Meta-analysis

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Systematic review shows ZnO improves rumen function and productivity in ruminants, suggesting benefits for sustainable agriculture.

This research aims to quantitatively assess the impact of zinc oxide supplementation on fermentation characteristics and productivity in ruminants.
Conducted a meta-analysis of 17 studies from 1971 to 2025
Evaluated effects of ZnO on rumen fermentation and nutrient utilization
Analyzed data using random-effects models and assessed publication bias
ZnO supplementation reduced methane production (SMD = −1.281; 95% CI: −1.818 to −0.743; P<0.001)
Increased propionate concentration (SMD = 0.521; P=0.026) and metabolizable energy (SMD = 2.034; P<0.001)
Improved daily gain (SMD = 0.565; P=0.004) and dry matter digestibility (SMD = 9.944; P<0.001)

Hidayat et al. (2026) studied this question.

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