Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 1961Journal of BacteriologyOpen Access

Antigenic Studies of Candida

View Full Paper
Ask AI
Bookmark
Share

Authors

HHH. F. HasencleverNational Institutes of HealthWMWilliam O. MitchellNational Institutes of Health

Discussion

Loading...

Member takes

Overview

Serological study reveals two distinct antigenic groups in Candida albicans isolates, indicating fundamental antigenic diversity within the species.

Key Points

  • To determine whether antigenic diversity exists among strains of Candida albicans using tube agglutination and serum adsorption techniques.
  • Screened 71 isolates of Candida albicans using tube agglutination tests with cross-adsorbed rabbit antisera.
  • Evaluated 35 strains using reciprocal cross-adsorptions with rabbit antisera raised against six representative isolates (three per group).
  • Confirmed species identification across all isolates by assessing chlamydospore formation, fermentation, and carbohydrate assimilation.
  • Classified 71 screened isolates into two groups: 38 strains agglutinated at dilutions of 1:240 to 1:480 (group A), whereas 33 strains failed to agglutinate at 1:30 (group B).
  • Heterologous adsorption of group A antisera retained agglutinating capacity for homologous strains, whereas adsorption with either group A or group B strains eliminated all agglutinating activity from group B antisera.

Cite This Study

Hasenclever et al. (1961) studied this question.

synapsesocial.com/papers/6a6faa398031ec7bb1dbe03dhttps://doi.org/10.1128/jb.82.4.570-573.1961
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An Immunologic Comparison of Twelve Strains of Cryptococcus neoformans (Torula histolytica).1949 · 87 citations
  2. 2Studies on the Immunologic Relationships among Various Species of the Genus Candida (Monilia)1942 · 24 citations