Why the study?
COVID-19 survivors face an increased risk of cardiovascular diseases 1 year after infection, but the underlying biological mechanisms remain unclear.
Does severe COVID-19 infection lead to sympathetic overdrive, vascular dysfunction, cardiac morpho-functional changes, and impaired exercise capacity in survivors compared to controls?
Population
19 severe COVID-19 survivors and 19 well-matched controls
Comparison
Severe COVID-19 survivors vs well-matched controls
Design
Case-control study
Follow-up
~3 months after hospital discharge
Authors
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May warrant CV surveillance in COVID-19 survivors; leaves open whether abnormalities predict events or respond to therapy.
Does severe COVID-19 infection lead to sympathetic overdrive, vascular dysfunction, cardiac morpho-functional changes, and impaired exercise capacity in survivors compared to controls?
Severe COVID-19 survivors exhibit significant mid-term cardiovascular sequelae, including sympathetic overactivation, vascular dysfunction, and reduced exercise capacity at 3 months post-discharge.
Faria et al. (2022) studied this question.
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