Why the study?
Does sodium dextrothyroxine affect the clotting mechanism and anticoagulant dosage requirements in patients receiving anticoagulants?
Population
14 patients (7 males, 7 females) receiving anticoagulants, 11 of whom were attending an anticoagulant clinic
Design
Cohort
Authors
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May alter anticoagulant dosing; cohort data leave open need for randomized confirmation before practice change.
Does sodium dextrothyroxine affect the clotting mechanism and anticoagulant dosage requirements in patients receiving anticoagulants?
This study investigates the interaction between the cholesterol-lowering agent sodium dextrothyroxine and anticoagulants, specifically its effect on the clotting mechanism and dosage requirements.
Owens et al. (1962) studied this question.
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