Why the study?
Does a family history of essential hypertension or premature myocardial infarction influence the longitudinal trajectories of systolic blood pressure and left ventricular mass in youth?
Population
745 subjects for SBP analysis and 687 subjects for LVM analysis, with approximately equal proportions of…
Comparison
Positive family history of essential… vs Negative family history of essential…
Design
Cohort
Follow-up
10 years
Authors
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May support intensified BP monitoring in youth with familial hypertension; hypothesis-generating for independent effects on LVM beyond BMI.
Does a family history of essential hypertension or premature myocardial infarction influence the longitudinal trajectories of systolic blood pressure and left ventricular mass in youth?
A family history of essential hypertension, but not premature MI, is associated with higher systolic blood pressure trajectories and left ventricular mass in youth, highlighting early genetic susceptibility to hypertension.
Dekkers et al. (2003) studied this question.
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