July 1, 1980HeartOpen Access

Haemodynamic and electrocardiographic effects of frusemide during supine exercise in patients with angina pectoris.

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Why the study?

Does furosemide improve haemodynamic, electrocardiographic, and symptomatic responses to exercise in patients with coronary artery disease?

Structured PICO

Does furosemide improve haemodynamic, electrocardiographic, and symptomatic responses to exercise in patients with coronary artery disease?

Population

19 patients with documented coronary artery disease who experienced angina, ST segment depression, and raised pulmonary artery wedge pressures during a control exercise period

Intervention

Furosemide 40 mg administered intravenously (n=12) or orally (n=7), followed by significant diuresis (>400 ml) before repeating the exercise test

Comparator

Control exercise period before furosemide administration (within-subject comparison)

Outcome

Haemodynamic, electrocardiographic, and symptomatic response to exercisesurrogate

Discussion

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Implication

Furosemide effects on exercise responses in CAD remain uncertain; leaves open any clinical role pending randomized trials.

Cite This Study

Nechwatal et al. (1980) studied this question.

synapsesocial.com/papers/6a6faeb8ac440176ef285713 https://doi.org/10.1136/hrt.44.1.67

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Haemodynamic and electrocardiographic effects of frusemide during supine exercise in patients with angina pectoris.

Structured PICO

Discussion

Implication

Cite This Study

Haemodynamic and electrocardiographic effects of frusemide during supine exercise in patients with angina pectoris.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider