What question did this study set out to answer?

To identify and evaluate the distribution of hepatitis B virus (HBV) genotypes and sub-genotypes across the general adult population nationwide.

July 29, 2020BMC Infectious DiseasesOpen Access

Distribution of hepatitis B virus genotypes in the general population of Myanmar via nationwide study

View Full Paper

Ask AI

Bookmark

Authors

YKYi Yi KyawMyanmar Oxford Clinical Research Unit ALAye Aye LwinNg Teng Fong General Hospital KAKhin Saw AyeMinistry of Health and Sports

Discussion

Member takes

Implication

Cross-sectional study reveals the predominance of hepatitis B virus genotype C in adults, highlighting key viral targets for regional disease surveillance.

Key Points

To identify and evaluate the distribution of hepatitis B virus (HBV) genotypes and sub-genotypes across the general adult population nationwide.
Screened 5,547 adults across seven states, seven regions, and the Nay Pyi Taw Union Territory in Myanmar for Hepatitis B Surface antigen (HBsAg) using an immunochromatographic test.
Identified HBV DNA in 153 of 353 HBsAg-positive samples via polymerase chain reaction targeting the Pre-S region.
Conducted bidirectional partial genome sequencing on the 153 PCR-positive samples and determined genotypes using the NCBI genotyping tool.
Detected three HBV genotypes: genotype C was the most prevalent at 66.7%, followed by genotype D at 32.0%, and genotype B at 1.3%.
Identified seven sub-genotypic variants—B4 and B5 in genotype B; C1, C5, and C7 in genotype C; and D3 and D6 in genotype D—with sub-genotype C1 predominating across all regions.

Cite This Study

Kyaw et al. (2020) studied this question.

synapsesocial.com/papers/6a6faef4e5469ee92be08ce4 https://doi.org/10.1186/s12879-020-05269-z

View Full Paper

Ask AI

Bookmark

Implication

Cross-sectional study reveals the predominance of hepatitis B virus genotype C in adults, highlighting key viral targets for regional disease surveillance.

Distribution of hepatitis B virus genotypes in the general population of Myanmar via nationwide study

Discussion

Member takes

Implication

Key Points

Cite This Study

Distribution of hepatitis B virus genotypes in the general population of Myanmar via nationwide study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider