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October 8, 2004Scandinavian Journal of Infectious Diseases

A nosocomial sapovirus-associated outbreak of gastroenteritis in adults

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Why the study?

Does HAART improve viral load, CD4 count, and mortality in HIV-infected patients in Greenland compared to the general population?

Population

103 HIV-infected patients in Greenland followed in health clinics since 1995, 91% Inuit, 81% heterosexually…

Comparison

Highly active antiretroviral therapy (HAART) vs Age- and gender-matched general population…

Design

Cohort

Authors

PJPeter JohanssonUppsala UniversityKBKatarina BergentoftLund UniversityPLPer Anders LarssonProver Technology (Sweden)

Discussion

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Implication

Excess mortality persists in HAART-treated Greenlandic HIV patients; leaves open whether targeted interventions can close the survival gap.

Structured PICO

Does HAART improve viral load, CD4 count, and mortality in HIV-infected patients in Greenland compared to the general population?

P
Population
103 HIV-infected patients in Greenland followed in health clinics since 1995, 91% Inuit, 81% heterosexually infected, and 10,300 age- and gender-matched population controls.
I
Intervention
Highly active antiretroviral therapy (HAART)
C
Comparator
Age- and gender-matched general population controls
O
Outcome
Effectiveness of HAART on CD4 positive cell count, viral load (VL), and mortalityhard clinical

Despite free access to healthcare and HAART, HIV-infected patients in Greenland continue to experience suboptimal viral suppression and excess mortality compared to the general population.

Cite This Study

Johansson et al. (2004) studied this question.

synapsesocial.com/papers/6a6faf2a5d37378ac1dcbdbfhttps://doi.org/10.1080/00365540410020974
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Also Consider

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  3. 3Electron microscopy and the investigation of new infectious diseases2003 · 18 citations
  4. 4Surveillance of Viral Gastroenteritis in Japan: Pediatric Cases and Outbreak Incidents2000 · 147 citations