Why the study?
Does pretreatment hepatitis C virus RNA titer predict serum ALT response to interferon-beta therapy in patients with chronic hepatitis C?
Population
50 chronic hepatitis C patients treated with interferon-beta
Design
Cohort
Authors
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Lower HCV RNA titer was associated with interferon response; hypothesis-generating for titer as predictor but should not yet guide therapy in chronic hepatitis C.
Does pretreatment hepatitis C virus RNA titer predict serum ALT response to interferon-beta therapy in patients with chronic hepatitis C?
Pretreatment serum level of hepatitis C virus RNA is a more important predictor of ALT response to interferon therapy than virus genotype in patients with chronic hepatitis C.
Kobayashi et al. (1993) studied this question.
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