Retrospective study reveals independent risk factors for cage migration in lumbar fusion patients, indicating strong potential for personalized surgical planning.
Objective Posterior lumbar interbody fusion (PLIF) is widely used for lumbar diseases, but cage migration (CM) remains a frequent and serious complication. Identifying risk factors for CM is crucial to improving surgical outcomes. Methods A retrospective analysis was conducted on 517 patients who underwent PLIF surgery at Nanyang Central Hospital between January 2020 and December 2024. Patients were divided into CM ( n = 46) and non-CM groups ( n = 471) based on postoperative imaging findings. Demographic characteristics, intraoperative parameters, and radiographic data were collected. Univariate and multivariate logistic regression analyses were performed to identify independent predictors of CM. A nomogram model was constructed based on significant variables, and its performance was evaluated using a receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). Results The overall incidence of CM was 8.9%. Univariate analysis revealed significant differences in the rates of osteoporosis, spondylolisthesis, Modic changes, PI-LL mismatch, and preoperative hemoglobin levels between the two groups ( p < 0.05). Multivariate analysis identified osteoporosis (OR = 4.186, 95% CI: 1.654–11.421), spondylolisthesis (OR = 8.199, 95% CI: 3.191–22.937), Modic type I change (OR = 8.279, 95% CI: 3.135–23.891), PI-LL (OR = 1.306, 95% CI: 1.192–1.453), and preoperative hemoglobin level (OR = 0.822, 95% CI: 0.753–0.888) as independent risk factors for CM. A nomogram incorporating these five variables showed good discrimination (AUC=0.874, 95% CI: 0.813–0.935) and calibration (Hosmer–Lemeshow test, χ 2 = 7.530, P = 0.481). DCA demonstrated a favorable net benefit across a threshold probability range of 0.05 to 0.81. Conclusion The developed nomogram model may assist clinicians in preoperative risk stratification and in formulating personalized surgical and perioperative strategies.
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Ma et al. (2026) studied this question.
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