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September 1, 1991Journal of Clinical MicrobiologyOpen Access

A novel group A rotavirus G serotype: serological and genomic characterization of equine isolate FI23

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Population

Equine rotavirus isolate FI23

Comparison

Cross-neutralization and VP7 sequence… vs G3 rotaviruses

Design

Preclinical

Authors

GBGlenn F. BrowningThe University of MelbourneTFT. A. FitzgeraldMoredun Research InstituteRCRachel M. ChalmersSingleton Hospital

Discussion

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Implication

Supports provisional G14 classification for equine rotavirus FI23; hypothesis-generating for antigenic surveillance and vaccine cross-protection.

Structured PICO

P
Population
Equine rotavirus isolate FI23
I
Intervention
Cross-neutralization and VP7 sequence determination
C
Comparator
G3 rotaviruses
O
Outcome
Serotype classification and amino acid sequence differences in VP7 antigenic regions

Identifies equine rotavirus FI23 as a novel G serotype (G14) based on serological and genomic characterization.

Cite This Study

Browning et al. (1991) studied this question.

synapsesocial.com/papers/6a6fb25ca2d7cf2e39c294aahttps://doi.org/10.1128/jcm.29.9.2043-2046.1991
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serotypic Similarity and Diversity of Rotaviruses of Mammalian and Avian Origin as Studied by Plaque-Reduction Neutralization1984 · 420 citations
  2. 2A candidate for a new serotype of human rotavirus1985 · 221 citations
  3. 3Nucleotide sequence of the gene encoding the serotype-specific antigen of human (Wa) rotavirus: comparison with the homologous genes from simian SA11 and UK bovine rotaviruses1984 · 55 citations
  4. 4Infection immunity of piglets to either VP3 or VP7 outer capsid protein confers resistance to challenge with a virulent rotavirus bearing the corresponding antigen1988 · 154 citations
  5. 5Nucleotide sequence of the gene encoding the serotype-specific glycoprotein of UK bovine rotavirus1983 · 80 citations