Long-term results of patients with onychomycosis treated with itraconazole.

We studied the long-term results of 88 patients treated with itraconazole either with continuous or pulse therapy. No differences were noted in the treatment results between these two groups. Thirty-six weeks after cessation of a 12-week drug therapy total clinical cure was achieved in 35% of these patients with 93% negative culture. At a follow-up at week 104 the total clinical cure was 39%, with negative culture in 57%.