Population
Saccharomyces cerevisiae (yeast) cells
Comparison
Mutation of MDM20 gene and overexpression of… vs Wild-type yeast or other mutant strains
Design
Preclinical
Authors
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Hypothesis-generating for actin roles in mitochondrial inheritance; leaves open relevance beyond yeast models.
Identifies the MDM20 gene in yeast as necessary for mitochondrial inheritance and actin cytoskeleton organization.
Hermann et al. (1997) studied this question.
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