The effect of environmental pH on the growth of normal and malignant cells

Data have been presented with respect to the widely varying pH optima for the growth of a number of normal and transformed human, mouse, monkey, hamster, rabbit and rat cell lines. At that optimum, differences between normal and transformed cells with respect to maximum population densities tended to become less prominent. Other differences (serum requirement, long‐term viability of cultures) were not demonstrably pH‐dependent.