January 1, 1999Cellular Physiology and Biochemistry

Biophysical Properties and Molecular Basis of Cardiac Rapid and Slow Delayed Rectifier Potassium Channels

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Population

Cardiac rapid and slow delayed rectifier potassium channels (HERG and KvLQT1/minK K(+) channels)

Design

Review

Authors

JMJohn S. MitchesonUniversity of Padua MSMichael C. SanguinettiElectrophysiology

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Implication

Reinforces channel roles in LQTS risk assessment; leaves open integration with emerging targeted therapies.

Structured PICO

Population

Cardiac rapid and slow delayed rectifier potassium channels (HERG and KvLQT1/minK K(+) channels)

This review provides foundational knowledge on the molecular basis and biophysical properties of cardiac potassium channels, which are critical for understanding the pathophysiology of long QT syndrome and drug-induced arrhythmias.

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Mitcheson et al. (1999) studied this question.

synapsesocial.com/papers/6a6fbd64febe604dd708971c https://doi.org/10.1159/000016317

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Biophysical Properties and Molecular Basis of Cardiac Rapid and Slow Delayed Rectifier Potassium Channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Biophysical Properties and Molecular Basis of Cardiac Rapid and Slow Delayed Rectifier Potassium Channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider