⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

June 8, 1999Proceedings of the National Academy of SciencesOpen Access

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

View Full Paper

Ask AI

Bookmark

Share

Authors

SSScott H. SoderlingDuke University SBSharon J. BayugaUniversity of Washington JBJoseph A. BeavoUniversity of Washington

Discussion

Loading...

Member takes

Implication

PDE10A defines a new dual-specificity PDE family; leaves open its roles in cyclic nucleotide signaling and therapeutic targeting.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Soderling et al. (1999) studied this question.

synapsesocial.com/papers/6a6fbd76e5469ee92be097c6 https://doi.org/10.1073/pnas.96.12.7071

View Full Paper

Ask AI

Bookmark

Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Identification of Key Amino Acids in a Conserved cGMP-binding Site of cGMP-binding Phosphodiesterases1996 · 72 citations
2Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues.1982 · 327 citations
3Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases.1990 · 173 citations
4Noncatalytic cGMP-binding sites of amphibian rod cGMP phosphodiesterase control interaction with its inhibitory gamma-subunits. A putative regulatory mechanism of the rod photoresponse.1992 · 131 citations
5An Essential Aspartic Acid at Each of Two Allosteric cGMP-binding Sites of a cGMP-specific Phosphodiesterase1995 · 96 citations