Discusses the SPRINT trial outcomes in the context of the J-curve phenomenon, favoring a systolic blood pressure target below 120 mmHg.
Highlights continuous mortality risk across BP spectrum; leaves open optimal treatment thresholds pending randomized data.
Early observational blood pressure (BP) data from untreated persons undergoing insurance physicals demonstrated that mortality was directly proportional to BP, even in the normal range. However, so...
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Kjeldsen et al. (2015) studied this question.