A novel mathematical method using biplane coronary cineangiograms can validly estimate regional cardiac wall deformation and stress without the need for implanted markers.
Supports preclinical validation of marker-free deformation analysis; leaves open human translation before clinical consideration.
A new mathematical method was developed to estimate the local epicardial deformation, wall thickness, and the regional circumferential and longitudinal wall stress using biplane coronary cineangiograms. In this method, the motion images of the coronary artery bifurcation points were used as natural landmarks for the kinematic analysis of the ventricular deformation. In four dogs and a normal patient's coronary cineangiograms, the estimation results show the validity of the present analysis, compared to the experimental results based upon the implanted markers. Thus, the present method provides a new method of evaluating the regional wall deformation and wall stress together with the blood vessel conditions using the coronary cineangiography procedure.
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Kim et al. (1985) studied this question.
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