Why the study?
Are the Surviving Sepsis Campaign and Early Goal Directed Therapy recommendations applicable to pregnant women with serious infection?
Are the Surviving Sepsis Campaign and Early Goal Directed Therapy recommendations applicable to pregnant women with serious infection?
Standardized management protocols for severe sepsis, including Early Goal Directed Therapy, have relevance and applicability to pregnant patients.
May support applying most sepsis protocols to pregnant women; leaves open need for pregnancy-specific trials.
Sepsis is a major cause of serious morbidity and mortality in pregnant women and their babies. Conventional management has evolved over many years. Improved understanding of the underlying pathophysiology and randomized clinical trials have led to recommendations for the formalization and standardization of the management of severe sepsis in non-pregnant patients. Most of these recommendations are applicable to pregnancy. The Surviving Sepsis Campaign and Early Goal Directed Therapy have relevance to the care of pregnant women with serious infection and are reviewed here.
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Joseph et al. (2009) studied this question.
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