Why the study?
Does COPD-heart failure overlap impair cardiac output, muscle blood flow, and endurance exercise tolerance more than either condition alone?
Population
59 participants including 16 with COPD-heart failure overlap, 16 FEV1-matched COPD patients, 15 ejection…
Comparison
Cycle ergometer exercise tests at 20% and 80%… vs Comparisons among overlap, COPD alone, heart…
Design
Cross-sectional
Authors
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Overlap patients may face additive exercise limits; leaves open whether hemodynamic targets improve tolerance in prospective trials.
Does COPD-heart failure overlap impair cardiac output, muscle blood flow, and endurance exercise tolerance more than either condition alone?
COPD and heart failure have an additive effect in decreasing exercising cardiac output and skeletal muscle perfusion, leading to significantly lower exercise tolerance than either condition alone.
Oliveira et al. (2016) studied this question.
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