What question did this study set out to answer?

To determine the effectiveness of glucocorticoid treatment in alleviating symptoms and reducing healthcare utilization in children diagnosed with croup.

September 4, 1999BMJOpen Access

The effectiveness of glucocorticoids in treating croup: meta-analysis

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Authors

MAMonica AusejoMadrid Health Service ASAmets SáenzInstituto de Salud Carlos III BPB PhamUniversity Health Network

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Implication

Meta-analysis reveals reduced symptom severity and shorter hospital stays with glucocorticoids in children with croup, indicating significant therapeutic benefit.

Key Points

To determine the effectiveness of glucocorticoid treatment in alleviating symptoms and reducing healthcare utilization in children diagnosed with croup.
Meta-analysis of 24 randomized controlled trials evaluating glucocorticoids (such as dexamethasone and budesonide) in pediatric croup.
Assessed croup severity scores, frequency of cointerventions (adrenaline/epinephrine, antibiotics, or supplemental glucocorticoids), and duration of stay in emergency departments or inpatient wards.
Glucocorticoid treatment improved croup severity scores at 6 hours (effect size −1.0, 95% CI −1.5 to −0.6) and at 12 hours (−1.0, 95% CI −1.6 to −0.4), but the difference was not significant at 24 hours (−1.0, 95% CI −2.0 to 0.1).
Adrenaline treatments decreased by 9% (95% CI 2% to 16%) in patients treated with budesonide and by 12% (95% CI 4% to 20%) in those treated with dexamethasone.
Emergency department stay was reduced by 11 hours (95% CI −18 to 4 hours) and inpatient hospital stay was reduced by 16 hours (95% CI −31 to 1 hour).

Cite This Study

Ausejo et al. (1999) studied this question.

synapsesocial.com/papers/6a6fc9052fdcb5703edb4f09 https://doi.org/10.1136/bmj.319.7210.595

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Implication

Meta-analysis reveals reduced symptom severity and shorter hospital stays with glucocorticoids in children with croup, indicating significant therapeutic benefit.

The effectiveness of glucocorticoids in treating croup: meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

The effectiveness of glucocorticoids in treating croup: meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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