Population
Mice used as models for mammalian genetic modifications to mimic and analyse cardiovascular pathology
Design
Review
Authors
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Mouse parameter variability warrants cautious model interpretation; leaves open standardization needs for reproducible cardiovascular phenotyping.
This review highlights the utility and challenges of cardiovascular phenotyping in genetically modified mouse models, emphasizing the need for awareness of physiological parameter variations.
Pieter A. Doevendans (1998) studied this question.
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