Why the study?
Does benazepril improve survival and delay cardiac events in dogs with asymptomatic mitral valve disease?
Population
141 dogs with ISACHC class Ia degenerative mitral valve disease and moderate-to-severe mitral regurgitation
Comparison
Benazepril with no other cardiac medication from… vs No cardioactive treatment until occurrence of…
Design
Cohort
Follow-up
median 3.3 years in treated group and 1.9 years in…
Authors
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May support benazepril in non-CKCS dogs with asymptomatic MVD; hypothesis-generating and requires RCTs before practice change.
Does benazepril improve survival and delay cardiac events in dogs with asymptomatic mitral valve disease?
Benazepril may prolong survival and delay cardiac events in certain breeds of dogs with asymptomatic degenerative mitral valve disease and moderate-to-severe mitral regurgitation.
Pouchelon et al. (2008) studied this question.
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