Diagnostic ultrasound provides an accurate method for the detection of early pregnancy and embryonic loss in macaque species. A developing gestational sac (GS) may be observed on gestational day (GD) 14-15 with positive identification on GD 16-18. Visualization of the yolk sac, embryo, and developing heart on GD 21-25 confirms pregnancy. Continuous observations during embryogenesis provide useful information when assessing the teratogenic potential of a variety of agents.
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Tarantal et al. (1988) studied this question.
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