Why the study?
Does combination therapy with an ACE inhibitor and amlodipine reduce urinary albumin excretion in hypertensive type II diabetic patients with microalbuminuria?
Population
30 hypertensive, type II diabetic patients with microalbuminuria
Comparison
Combination therapy with an ACE inhibitor plus… vs ACE inhibitor alone for 32 weeks
Design
Cohort
Follow-up
32 weeks
Authors
Loading...
May support adding amlodipine to ACE inhibitor for microalbuminuria in diabetic hypertension; hypothesis-generating and needs RCT confirmation.
Does combination therapy with an ACE inhibitor and amlodipine reduce urinary albumin excretion in hypertensive type II diabetic patients with microalbuminuria?
Combination therapy with an ACE inhibitor and amlodipine provides greater reduction in blood pressure and urinary albumin excretion compared to ACE inhibitor monotherapy in hypertensive diabetic patients with microalbuminuria.
Shigihara et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: