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September 6, 1999The Journal of Cell BiologyOpen Access

Human Bubr1 Is a Mitotic Checkpoint Kinase That Monitors Cenp-E Functions at Kinetochores and Binds the Cyclosome/APC

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Authors

GCGordon K. ChanUniversity of AlbertaSJSandra A. JablonskiGeorgetown UniversityVSValery SudakinGlaxoSmithKline (United States)

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Chan et al. (1999) studied this question.

synapsesocial.com/papers/6a6fdaefa7fbea1e4407dd70https://doi.org/10.1083/jcb.146.5.941
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation1998 · 598 citations
  2. 2Characterization of the Kinetochore Binding Domain of CENP-E Reveals Interactions with the Kinetochore Proteins CENP-F and hBUBR11998 · 280 citations
  3. 3The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.1995 · 764 citations
  4. 4Budding Yeast Cdc20: A Target of the Spindle Checkpoint1998 · 569 citations