Why the study?
Does tinzaparin sodium reduce clinical clotting compared to unfractionated heparin in haemodialysis patients?
Population
23 haemodialysis patients
Comparison
Tinzaparin sodium for 6 months vs Unfractionated heparin (UFH) for 6 months
Design
Cohort
Follow-up
12 months (6 months per stage)
Authors
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Tinzaparin may reduce clotting versus UFH in HD; hypothesis-generating and requires RCTs before practice change.
Does tinzaparin sodium reduce clinical clotting compared to unfractionated heparin in haemodialysis patients?
Tinzaparin sodium is an effective and well-tolerated alternative to unfractionated heparin for haemodialysis, reducing clotting and improving dialysis adequacy, though at a 23% higher cost.
Sabry et al. (2008) studied this question.
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