Primary Splenic Neutropenia; A Newly Recognized Syndrome, Closely Related to Congenital Hemolytic Icterus and Essential Thrombocytopenic Purpura

Article1 June 1942PRIMARY SPLENIC NEUTROPENIA; A NEWLY RECOGNIZED SYNDROME, CLOSELY RELATED TO CONGENITAL HEMOLYTIC ICTERUS AND ESSENTIAL THROMBOCYTOPENIC PURPURAB. K. WISEMAN, F.A.C.P., CHARLES A. DOAN, F.A.C.P.B. K. WISEMAN, F.A.C.P.Search for more papers by this author, CHARLES A. DOAN, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-6-1097 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe spleen may no longer be regarded as an organ of complete mystery. Out of ancient and modern superstitious musings and the obscurity of an incomplete, controversial and largely hypothetical pathologic hematology have gradually emerged sufficient facts relating to splenic structure and functions to compare favorably with current knowledge of the other abdominal viscera. The pioneer work of Barcroft, McNee, Lord Dawson, and Krumbhaar, in creating sound fundamental concepts of physiologic splenic functions has been supplemented by thorough controlled studies of human pathologic splenic diseases, with improved technics by the clinical hematologists, Kaznelson, Frank, Dameshek, Doan and Wiseman among others....Bibliography1. WISEMANDOAN BKCA: A newly recognized granulopenic syndrome caused by excessive splenic leucolysis and successfully treated by splenectomy, Jr. Clin. Invest., 1939, xviii, 473. Google Scholar2. MOOREBIERBAUM CVOS: Chronic neutropenia treated by splenectomy, Internat. Clin., 1939, iii, 86-95. Google Scholar3. MUETHERMOORESTEWARTBROWN ROLTIWGO: Chronic granulocytopenia caused by excessive splenic lysis of granulocytes, Jr. Am. Med. Assoc., 1941, cxvi, 2255-2257. CrossrefGoogle Scholar4. WISEMANDOANWILSON BKCASJ: Present status of thrombocytopenic purpura, with special reference to diagnosis and treatment, Jr. Am. Med. Assoc., 1940, cxv, 8-13. Google Scholar5. DOANCURTISWISEMAN CAGMBK: Hemolytopoietic equilibrium and emergency splenectomy, Jr. Am. Med. Assoc., 1935, cv, 1567-1574. CrossrefGoogle Scholar6. FELTY AR: Chronic arthritis in adult, associated with splenomegaly and leucopenia, Bull. Johns Hopkins Hosp., 1924, xxxv, 16-20. Google Scholar7. HANRAHANMILLER EMSR: Effect of splenectomy in Felty's syndrome, Jr. Am. Med. Assoc., 1932, xcix, 1247-1249. CrossrefGoogle Scholar8. WILLIAMS RH: Felty's syndrome; report of case with necropsy findings, ANN. INT. MED., 1936, ix, 1247-1255. Google Scholar9. CRAVENS EB: Splenectomy in chronic arthritis associated with splenomegaly and leucopenia (Felty's syndrome), Jr. Am. Med. Assoc., 1934, cii, 823-826. CrossrefGoogle Scholar10. PRICESCHOENFELD AEJB: Felty's syndrome; report of case with complete postmortem findings, ANN. INT. MED., 1934, vii, 1230-1239. LinkGoogle Scholar11. FITZ-HUGHKRUMBHAAR TEB: Myeloid cell hyperplasia of bone marrow in agranulocytic angina, Am. Jr. Med. Sci., 1932, clxxxiii, 104-111. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: B. K. WISEMAN, F.A.C.P.; CHARLES A. DOAN, F.A.C.P.Affiliations: Columbus, Ohio*Received for publication January 16, 1942. 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LANGLEY, M.D.HypersplenismHYPERSPLENISM WITH ARTHRITISThe Anemic States: Their Causes and TreatmentThe cellular and humoral factors influencing constitutional resistance and the development and control of local lesionsSurgical Conditions of the SpleenSplenectomy in pregnancy: Its hematologic indications and obstetric managementSPLENIC NEUTRO-THROMBOPENIAHYPERSPLENISM: SOME PRELIMINARY OBSERVATIONSDiabetes mellitus, fibrocongestive splenomegaly (Banti’s syndrome) and infectious mononucleosisGranulocytopenic and Lymphocytopenic Hypersplenism Associated with Atrophic ArthritisBone Marrow Examination in Blood Disorders of Infants and ChildrenPrimary Splenic Granulocytopenia and LymphopeniaThe Differential Diagnosis of Splenomegaly of Adults 1 June 1942Volume 16, Issue 6 Page: 1097-1117 Keywords Hematology and oncology Neutropenia Spleen ePublished: 1 December 2008 Issue Published: 1 June 1942 PDF downloadLoading ...