Hypersplenism: Two Cases With Leg Ulcers Treated by Splenectomy

Case Reports1 June 1949HYPERSPLENISM: TWO CASES WITH LEG ULCERS TREATED BY SPLENECTOMYJOSEPH C. PEDEN JR., M.D.JOSEPH C. PEDEN JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-6-1248 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSplenomegaly is the common factor in a variety of syndromes of indefinite etiology in which leukopenia, anemia, and thrombocytopenia may be associated disorders. Splenomegaly and leukopenia in rheumatoid arthritis are well known under the name of Felty's syndrome. Chronic leg ulcers have frequently been described in splenomegalic syndromes, and we have recently encountered two cases presenting splenomegaly, atrophic arthritis, anemia, elevated basal metabolism rates, leukopenia with relative and absolute neutropenia, and chronic nonhealing leg ulcers.CASE REPORTSCase 1. 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CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Received for publication May 26, 1947.From the Department of Pathology, The Ellis Fischel State Cancer Hospital, Columbia, Missouri. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRetardation of colony growth of in vitro bone marrow culture using sera from patients with felty' syndrome, disseminated lupus erythematosus (sle), rheumatoid arthritis, and other disease statesHautmanifestationen rheumatischer KrankheitenThe variable features of Felty's syndromeFELTY'S SYNDROMEPhysiologie und Pharmakologie der HautDermatologische Ver�nderungen beim Felty-SyndromChronic leg ulcers in cryptogenetic splenomegalyUnterschenkelgeschw�re als Begleitsymptom des famili�ren h�molytischen Ikterus 1 June 1949Volume 30, Issue 6Page: 1248-1262KeywordsAnemiaNeutropeniaPlateletsRed blood cellsRheumatoid arthritisSplenectomySplenomegalyUlcersWeight gainWhite blood cells ePublished: 1 December 2008 Issue Published: 1 June 1949 PDF downloadLoading ...