Why the study?
Does two-dimensional echocardiography accurately assess segmental and global left ventricular function and correlate with clinical status in patients with acute myocardial infarction?
Does two-dimensional echocardiography accurately assess segmental and global left ventricular function and correlate with clinical status in patients with acute myocardial infarction?
Two-dimensional echocardiography is a useful technique for localizing and assessing left ventricular dyssynergy in acute myocardial infarction, correlating well with clinical and enzymatic markers of infarct severity.
Both segmental and global left ventricular performance were assessed simultaneously in 29 patients with acute myocardial infarction using two-dimensional echocardiography. Comparisons were made between left ventricular wall motion versus peak CK-MB, site of infarction, and occurrence of heart failure. Two-dimensional echocardiography identified areas of dyssynergy which corresponded to electrocardiographic areas of infarction in 89% of all cases. Patients with heart failure had more dyssynergic segments, and these segments manifested more severe dyssynergy than patients without heart failure. Patients with severe global dysfunction manifested higher peak CK-MB values, and those with anterior infarction had more global dyssynergy than did those patients with inferior infarction. These observations suggest that two-dimensional echocardiography is a useful technique for localization and assessment of segmental and global dyssynergy in acute myocardial infarction. Information so derived correlates with the clinical status of patients with acute myocardial infarction, and may offer important insights into both prognosis and treatment.
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Charuzi et al. (1983) studied this question.
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