The Disabilities Caused by Hypophysectomy and Their Repair

From results gained in an extensive series of investigations on the dog carried out in 1922 and earlier, Camus and Roussy,¹and Bailey and Bremer²concluded that the hypophysis exercises few of the functions that have been attributed to it. Camus and Roussy state, in answer to the question, What is the proper function of the hypophysis? "We would not know how to reply except by hypotheses." Bailey and Bremer likewise affirm, "But we must admit that we have little actual knowledge of its functional significance in the adult animal." Other investigators have in most cases considered that the so-called pituitary disorders, including obesity and not infrequently glycosuria and polyuria, are due to their operatively induced pituitary deficiency. Recently Roussy³has been will ing to grant that the rôle of the anterior pituitary in skeletal growth is well established, and Bremer⁴states that the pituitary is