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December 1, 1949The Journal of Experimental MedicineOpen Access

The Effect of the Size of the Inoculum and the Age of the Infection on the Curative Dose of Penicillin in Experimental Infections With Streptococci, Pneumococci, and Treponema Pallidum

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HEHarry EaglePeterborough City Hospital

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Harry Eagle (1949) studied this question.

synapsesocial.com/papers/6a6fe961febe604dd708bc06https://doi.org/10.1084/jem.90.6.595
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An Analysis of the Wilson-Worcester Method for Determining the Median Effective Dose of Pertussis Vaccine1948 · 12 citations
  2. 2RELATION OF THE SIZE OF THE INOCULUM AND THE AGE OF THE INFECTION TO THE CURATIVE DOSE OF PENICILLIN IN EXPERIMENTAL SYPHILIS, WITH PARTICULAR REFERENCE TO THE FEASIBILITY OF ITS PROPHYLACTIC USE1947 · 41 citations
  3. 3THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS1948 · 377 citations
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