What question did this study set out to answer?

To evaluate the safety and clinical outcomes of using deep hypothermia combined with surface cooling and limited cardiopulmonary bypass for corrective intracardiac surgery in neonates and infants.

May 1, 1971Circulation

Intracardiac Surgery in Neonates and Infants Using Deep Hypothermia with Surface Cooling and Limited Cardiopulmonary Bypass

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To evaluate the safety and clinical outcomes of using deep hypothermia combined with surface cooling and limited cardiopulmonary bypass for corrective intracardiac surgery in neonates and infants.
Treated 37 infants weighing under 10 kg with correctable congenital cardiac defects under halothane anesthesia.
Cooled infants via surface cooling blankets to a nasopharyngeal temperature of 26°C, followed by total body perfusion to achieve deep hypothermia at 22°C.
Performed intracardiac repair during total circulatory arrest averaging 48 minutes, followed by 20 minutes of perfusion rewarming to 32°C and surface rewarming to 36°C.
Overall survival was 89.2% (33 of 37 infants), including 25 successful repairs in infants aged between 8 days and 12 months.
Anatomical repairs included transposition of the great arteries (13 cases), tetralogy of Fallot (9 cases), total anomalous pulmonary venous connection (6 cases), ventricular septal defect (6 cases), and atrioventricular canal (3 cases).

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Implication

Clinical series reports 89% survival following deep hypothermic circulatory arrest in infants with congenital heart defects, indicating broad surgical utility.

Cite This Study

Barratt‐Boyes et al. (1971) studied this question.

synapsesocial.com/papers/6a6fe9662163a0a01bc4258b https://doi.org/10.1161/01.cir.43.5s1.i-25

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Implication

Clinical series reports 89% survival following deep hypothermic circulatory arrest in infants with congenital heart defects, indicating broad surgical utility.

Intracardiac Surgery in Neonates and Infants Using Deep Hypothermia with Surface Cooling and Limited Cardiopulmonary Bypass

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Discussion

Implication

Cite This Study

Intracardiac Surgery in Neonates and Infants Using Deep Hypothermia with Surface Cooling and Limited Cardiopulmonary Bypass

Key Points

Discussion

Implication

Cite This Study

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